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产品简介
英文名称 | Anti-ARRB1 Monoclonal Antibody |
别名 | ARB1;ARR1;β-Arrestin 1 |
宿主 | Mouse |
稀释比例 | WB 1:500. |
Gene ID | 408 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P49407 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 47kDa |
亚细胞定位 | Cell membrane Cell projection Cytoplasm Cytoplasmic vesicle Membrane Nucleus clathrin-coated pit pseudopodium |
免疫原 | Purified recombinant human ARRB1 protein fragments expressed in E.coli. |
亚型 | lgG2b |
性状 | 液体 |
纯化方法 | Affinity purification |
克隆号 | 1H4-F5-C11 |
背景资料 | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones,neurotransmitters, or sensory signals.Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors.Besides the central nervous system,it is expressed at high levels in peripheral blood leukocytes,and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.[provided by RefSeq,Jan 2011] |
克隆类型 | Monoclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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