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产品简介
| 英文名称 | Anti-FADD Monoclonal Antibody |
| 别名 | GIG3;MORT1 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:500. |
| Gene ID | 8772 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q13158 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 23kDa |
| 亚细胞定位 | Cytosol Nucleus Plasma Membrane |
| 免疫原 | Recombinant human FADD protein. |
| 亚型 | IgG1 |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 5E8-A7 |
| 背景资料 | The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals.Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor,tumor necrosis factor receptor,TNFRSF25,and TNFSF10/TRAIL-receptor,and thus it participates in the death signaling initiated by these receptors.Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein,which allows it to recruit caspase-8,and thereby activate the cysteine protease cascade.Knockout studies in mice also suggest the importance of this protein in early T cell development.[provided by RefSeq,Jul 2008] |
| Public Immunogen Range | Recombinant human FADD protein. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | Human |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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