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产品简介
| 英文名称 | Anti-PRKAB1 Monoclonal Antibody |
| 别名 | AMPK;AMPK beta 1;AMPK subunit beta 1;AMPKb;HAMPKb;PRKAB1 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. IHC 1:100. |
| Gene ID | 5564 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9Y478 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 30kDa |
| 亚细胞定位 | Cytosol Nucleus |
| 免疫原 | Purified recombinant human PRKAB1 protein fragments expressed in E.coli. |
| 亚型 | IgG2a |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 1A7-E11-E9 |
| 背景资料 | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK).AMPK is a heterotrimer consisting of an alpha catalytic subunit,and non-catalytic beta and gamma subunits.AMPK is an important energy-sensing enzyme that monitors cellular energy status.In response to cellular metabolic stresses,AMPK is activated,and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR),key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol.This subunit may be a positive regulator of AMPK activity.The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.[provided by RefSeq,Jul 2008] |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanMonkeyRatMouse |
| 应用 | WBIHCIPICC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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