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产品简介
| 英文名称 | Anti-Bax Monoclonal Antibody |
| 别名 | BCL2L4;Bax-protein;BAX_HUMAN;BAXA |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. |
| Gene ID | 581 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q07812 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 21kDa |
| 亚细胞定位 | Cytoplasm Cytoplasm Mitochondrion membrane Single-pass membrane protein |
| 免疫原 | Purified recombinant human Bax protein fragments expressed in E.coli |
| 亚型 | IgG2a |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 2B12-G6-H6 |
| 背景资料 | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. (provided by RefSeq, Jul 2008). |
| Public Immunogen Range | Purified recombinant human Bax protein fragments expressed in E.coli |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanMonkey |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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