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产品简介
| 英文名称 | Anti-MAPK8 Monoclonal Antibody |
| 别名 | JNK;JNK-46;JNK1;JNK1A2;JNK21B1/2;PRKM8;SAPK1;SAPK1c |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000. IF 1:100. |
| Gene ID | 5599 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P45983 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 48kDa |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Purified recombinant human MAPK8 protein fragments expressed in E.coli. |
| 亚型 | IgG2a |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 1A4-C5-F11 |
| 背景资料 | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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