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产品简介
英文名称 | Anti-ATP2A2 Polyclonal Antibody |
别名 | ATP2B;DAR;DD;SERCA2 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. |
Gene ID | 488 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P16615 |
蛋白分子量 | 115kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Endoplasmic reticulum membrane Multi-pass membrane protein Sarcoplasmic reticulum membrane |
免疫原 | Recombinant protein of human ATP2A2 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Public Immunogen Range | Recombinant protein of human ATP2A2 |
克隆类型 | Polyclonal Antibody |
交叉反应 | MouseRat |
应用 | WBIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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