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产品简介
| 英文名称 | Anti-LRP5 Polyclonal Antibody |
| 别名 | BMND1;EVR1;EVR4;HBM;LR3;LRP-5;LRP7;OPPG;OPS;OPTA1;VBCH2;LDL receptor related protein 5 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| Gene ID | 4041 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O75197 |
| 蛋白分子量 | 179kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Endoplasmic reticulum Membrane Single-pass type I membrane protein |
| 免疫原 | Recombinant protein of human LRP5 |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. |
| Public Immunogen Range | Recombinant protein of human LRP5 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | RatMouse |
| 应用 | WBIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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