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产品简介
| 英文名称 | Anti-TRAF3 Monoclonal Antibody |
| 靶标 | TRAF3 |
| 别名 | CAP-1;CAP1;CD40bp;CRAF1;IIAE5;LAP1 |
| 稀释比例 | WB 1:1000-4000. IHC 1:200-800. IF 1:50-500 . |
| Gene ID | 7187 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q13114 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 55/64kDa |
| 亚细胞定位 | Cytoplasm Endosome Mitochondrion |
| 免疫原 | Recombinant protein of human TRAF3 |
| 亚型 | IgG2a |
| 纯化方法 | Affinity purification |
| 性状 | 液体 |
| 背景资料 | TNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1 CD40 receptor-associated factor 1(CRAF1) CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1). TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases and plays a central role in the regulation of innate immune response. It modulates signaling pathways leading to the production of cytokines and interferon. As an essential constituent of several E3 ubiquitin-protein ligase complexes TRAF3 promote 'Lys-63'-linked ubiquitination of target proteins. Moreover TRAF3 undergoes both 'Lys-48'-linked and 'Lys-63'-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1 OTUB2 and OTUD5. |
| Public Immunogen Range | Recombinant protein of human TRAF3 |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WBIFIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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