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产品简介
英文名称 | Anti-BCL2L1 Polyclonal Antibody |
别名 | BCL-XL/S;BCL2L;BCLX;Bcl-X;PPP1R52 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. IP 1:50-100. |
Gene ID | 598 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q07817 |
蛋白分子量 | 26kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Cytoplasmic side Cytoplasmic vesicle Mitochondrion inner membrane Mitochondrion matrix Mitochondrion outer membrane Nucleus membrane Single-pass membrane protein centrosome cytoskeleton cytosol microtubule organizing center secretory vesicle synaptic vesicle membrane |
免疫原 | Recombinant protein of human BCL2L1 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. |
Public Immunogen Range | Recombinant protein of human BCL2L1 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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