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产品简介
| 英文名称 | Anti-CDKN1B Polyclonal Antibody |
| 别名 | CDKN1B;CDKN4;KIP1;MEN1B;MEN4;P27;KIP1;P27KIP1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:20-50. |
| Gene ID | 1027 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P46527 |
| 蛋白分子量 | 22kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Endosome Nucleus |
| 免疫原 | Recombinant protein of human CDKN1B |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). |
| Public Immunogen Range | Recombinant protein of human CDKN1B |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIFIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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