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产品简介
英文名称 | Anti-GRIN2A Polyclonal Antibody |
别名 | EPND;FESD;GluN2A;LKS;NMDAR2A;NR2A |
宿主 | Rabbit |
稀释比例 | WB 1:500-1000. IHC 1:50-200. |
Gene ID | 2903 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q12879 |
蛋白分子量 | 165kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cell junction Cell membrane Multi-pass membrane protein postsynaptic cell membrane synapse |
免疫原 | Recombinant protein of human GRIN2A |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. |
Public Immunogen Range | Recombinant protein of human GRIN2A |
克隆类型 | Polyclonal Antibody |
交叉反应 | MouseRat |
应用 | WBIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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