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产品简介
| 英文名称 | Anti-DSC1 Polyclonal Antibody |
| 别名 | CDHF1;DG2/DG3;Desmocollin-1;CDHF1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| Gene ID | 1823 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q08554 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 100/94kDa |
| 亚细胞定位 | Cell junction Cell membrane Single-pass type I membrane protein desmosome |
| 免疫原 | Recombinant protein of human DSC1 |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. |
| Public Immunogen Range | Recombinant protein of human DSC1 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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