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产品简介
英文名称 | Anti-LILRB2 Polyclonal Antibody |
别名 | CD85D;ILT-4;ILT4;LIR-2;LIR2;MIR-10;MIR10 |
宿主 | Rabbit |
稀释比例 | WB 1:1000-4000. |
Gene ID | 10288 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q8N423 |
蛋白分子量 | 65kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Membrane Single-pass type I membrane protein |
免疫原 | Recombinant protein of human LILRB2 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. |
Public Immunogen Range | Recombinant protein of human LILRB2 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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