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产品简介
| 英文名称 | Anti-TPMT Polyclonal Antibody |
| 别名 | TPMTD |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:10-100. |
| Gene ID | 7172 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P51580 |
| 蛋白分子量 | 28kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human TPMT |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. |
| Public Immunogen Range | Recombinant protein of human TPMT |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WBIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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