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产品简介
| 英文名称 | Anti-TYMS Polyclonal Antibody |
| 别名 | HST422;TMS;TS |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IF 1:50-200. |
| Gene ID | 7298 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P04818 |
| 蛋白分子量 | 36kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Mitochondrion Mitochondrion inner membrane Mitochondrion matrix Nucleus |
| 免疫原 | Recombinant protein of human TYMS |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. |
| Public Immunogen Range | Recombinant protein of human TYMS |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIFIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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