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产品简介
| 英文名称 | Anti-RASGRP1 Polyclonal Antibody |
| 别名 | CALDAG-GEFI;CALDAG-GEFII;RASGRP;V;hRasGRP1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-2000. |
| Gene ID | 10125 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O95267 |
| 蛋白分子量 | 90kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane Cytoplasm Endoplasmic reticulum membrane Golgi apparatus membrane Peripheral membrane protein cytosol |
| 免疫原 | Recombinant protein of human RASGRP1 |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). |
| Public Immunogen Range | Recombinant protein of human RASGRP1 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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