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产品简介
英文名称 | Anti-CDH4 Polyclonal Antibody |
别名 | CAD4;R-CAD;RCAD |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-200. |
Gene ID | 1002 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P55283 |
蛋白分子量 | 100kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cell membrane Single-pass type I membrane protein |
免疫原 | Recombinant protein of human CDH4 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. |
Public Immunogen Range | Recombinant protein of human CDH4 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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