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产品简介
英文名称 | Anti-FAM3B Polyclonal Antibody |
别名 | 2-21;C21orf11;C21orf76;ORF9;PANDER;PRED44 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:10-100. IF 1:50-200. |
Gene ID | 54097 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P58499 |
蛋白分子量 | 26kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Secreted |
免疫原 | Recombinant protein of human FAM3B |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome. |
Public Immunogen Range | Recombinant protein of human FAM3B |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | WBIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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