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产品简介
英文名称 | Anti-KDR Polyclonal Antibody |
别名 | CD309;FLK1;VEGFR;VEGFR2 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-200. |
Gene ID | 3791 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P35968 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 75/79/151kDa |
亚细胞定位 | Cell junction Cell membrane Cytoplasm Cytoplasmic vesicle Early endosome Endoplasmic reticulum Nucleus Secreted Single-pass type I membrane protein |
免疫原 | Recombinant protein of human KDR |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. |
Public Immunogen Range | Recombinant protein of human KDR |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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