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产品简介
英文名称 | Anti-TLR2 Polyclonal Antibody |
别名 | CD282;TIL4 |
宿主 | Rabbit |
稀释比例 | WB 1:200-500. IHC 1:50-200. IF 1:50-100. |
Gene ID | 7097 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O60603 |
蛋白分子量 | 90kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Membrane Single-pass type I membrane protein |
免疫原 | A synthetic peptide of human TLR2 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. |
Public Immunogen Range | A synthetic peptide of human TLR2 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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