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产品简介
英文名称 | Anti-IL1B Polyclonal Antibody |
别名 | IL-1;IL1-BETA;IL1F2;interleukin 1 beta;IL 1 beta |
宿主 | Rabbit |
稀释比例 | IF 1:50-200. |
Gene ID | 3553 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P01584 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 17/31kDa |
亚细胞定位 | Cytoplasm Cytoplasmic vesicle Lysosome Secreted autophagosome cytosol exosome |
免疫原 | Recombinant protein of human IL1B |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
Public Immunogen Range | Recombinant protein of human IL1B |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | IF |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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