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产品简介
| 英文名称 | Anti-CDH1 Polyclonal Antibody |
| 别名 | CADH1;Cadherin-1;CDHE;UVO;ECAD;Arc-1;CD324;LCAM |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-1000. |
| Gene ID | 999 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P12830 |
| 蛋白分子量 | 97kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell junction Cell membrane Endosome Golgi apparatus Single-pass type I membrane protein trans-Golgi network |
| 免疫原 | A synthetic peptide of human CDH1 |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. |
| Public Immunogen Range | A synthetic peptide of human CDH1 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Mouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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