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产品名称
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起订数量
产品简介
英文名称 | Anti-HR Polyclonal Antibody |
别名 | ALUNC;AU;HSA277165;HYPT4;MUHH;MUHH1 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-200. |
Gene ID | 55806 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O43593 |
蛋白分子量 | 127kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Nucleus |
免疫原 | Recombinant protein of human HR |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. |
Public Immunogen Range | Recombinant protein of human HR |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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