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产品名称
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产品简介
英文名称 | Anti-RASSF1 Polyclonal Antibody |
别名 | 123F2;NORE2A;RASSF1A;RDA32;REH3P21 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IF 1:50-200. |
Gene ID | 11186 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q9NS23 |
蛋白分子量 | 39kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Nucleus Nucleus centrosome cytoskeleton microtubule organizing center spindle spindle pole |
免疫原 | Recombinant protein of human RASSF1 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Public Immunogen Range | Recombinant protein of human RASSF1 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanMouse |
应用 | WBIF |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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