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产品简介
英文名称 | Anti-HRAS Polyclonal Antibody |
别名 | HRAS;C-BAS/HAS;C-H-RAS;C-HA-RAS1;CTLO;H-RASIDX;HAMSV;HRAS1;RASH1;p21ras;GTPase HRas |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IF 1:50-200. |
Gene ID | 3265 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P01112 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 19/21kDa |
亚细胞定位 | Cell membrane Cytoplasm Golgi apparatus Membrane Nucleus |
免疫原 | Recombinant protein of human HRAS |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. |
Public Immunogen Range | Recombinant protein of human HRAS |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIF |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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