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产品简介
英文名称 | Anti-BCL2L11 Polyclonal Antibody |
别名 | BAM;BIM;BOD |
宿主 | Rabbit |
稀释比例 | IHC 1:50-100. |
Gene ID | 10018 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O43521 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 22/13/19/9/4kDa |
亚细胞定位 | Endomembrane system Mitochondrion Peripheral membrane protein |
免疫原 | Recombinant protein of human BCL2L11 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. |
Public Immunogen Range | Recombinant protein of human BCL2L11 |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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