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产品简介
英文名称 | Anti-SNX13 Polyclonal Antibody |
别名 | RGS-PX1 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IF 1:50-200 |
Gene ID | 23161 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q9Y5W8 |
蛋白分子量 | 112kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasmic side Early endosome membrane Peripheral membrane protein |
免疫原 | Recombinant protein of human SNX13 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. |
Public Immunogen Range | Recombinant protein of human SNX13 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanMouse |
应用 | WBIF |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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