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产品简介
| 英文名称 | Anti-COMT Polyclonal Antibody |
| 别名 | HEL-S-98n |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000.; IP 1:50-100. |
| Gene ID | 1312 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P21964 |
| 蛋白分子量 | 30kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane Cytoplasm Extracellular side Single-pass type II membrane protein |
| 免疫原 | Recombinant protein of human COMT |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. |
| Public Immunogen Range | Recombinant protein of human COMT |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WBIP |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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