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产品简介
英文名称 | Anti-IL6R Polyclonal Antibody |
别名 | CD126;IL-6R-1;IL-6RA;IL6Q;IL6RA;IL6RQ;gp80 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. |
Gene ID | 3570 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P08887 |
蛋白分子量 | 52kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Basolateral cell membrane Secreted Single-pass type I membrane protein |
免疫原 | Recombinant protein of human IL6R |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. |
Public Immunogen Range | Recombinant protein of human IL6R |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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