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产品名称
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产品简介
英文名称 | Anti-TFPI Polyclonal Antibody |
别名 | EPI;Extrinsic pathway inhibitor;LACI;TFI;TFPI;TFPI1 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IF 1:50-200. |
Gene ID | 7035 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P10646 |
蛋白分子量 | 35kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Endoplasmic reticulum Membrane Microsome Secreted |
免疫原 | Recombinant protein of human TFPI |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. |
Public Immunogen Range | Recombinant protein of human TFPI |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIF |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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