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产品简介
英文名称 | Anti-CHRNA4 Polyclonal Antibody |
别名 | BFNC;EBN;EBN1;NACHR;NACHRA4;NACRA4 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. |
Gene ID | 1137 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P43681 |
蛋白分子量 | 70kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cell junction Cell membrane Lipid-anchor Multi-pass membrane protein postsynaptic cell membrane synapse |
免疫原 | Recombinant protein of human CHRNA4 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. |
Public Immunogen Range | Recombinant protein of human CHRNA4 |
克隆类型 | Polyclonal Antibody |
交叉反应 | Mouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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