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产品简介
英文名称 | Anti-SLC22A5 Polyclonal Antibody |
别名 | CDSP;OCTN2 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IF 1:50-200. |
Gene ID | 6584 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O76082 |
蛋白分子量 | 63kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Membrane Multi-pass membrane protein |
免疫原 | Recombinant protein of human SLC22A5 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants. |
Public Immunogen Range | Recombinant protein of human SLC22A5 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanMouse |
应用 | WBIF |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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