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产品简介
英文名称 | Anti-CFL1 Polyclonal Antibody |
别名 | CFL;HEL-S-15;CFL1;Cofilin 1;cofilin 1 (non muscle);Cofilin;non muscle isoform;p18 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
Gene ID | 1072 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P23528 |
蛋白分子量 | 19kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cell membrane Cell projection Cytoplasm Cytoskeleton Membrane Nucleus |
免疫原 | A synthetic peptide of human CFL1 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
Public Immunogen Range | A synthetic peptide of human CFL1 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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