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产品名称
起订量
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产品简介
英文名称 | Anti-VCL Polyclonal Antibody |
别名 | CMD1W;CMH15;HEL114;MV;MVCL;Metavinculin;Vinculin |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-200. |
Gene ID | 7414 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P18206 |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
蛋白分子量 | 124/117/25kDa |
亚细胞定位 | Cell junction Cell membrane Cytoplasm Cytoplasmic side Peripheral membrane protein adherens junction cytoskeleton focal adhesion |
免疫原 | Recombinant protein of human VCL |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. |
Public Immunogen Range | Recombinant protein of human VCL |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanMouse |
应用 | WBIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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