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产品简介
英文名称 | Anti-AKR1C3 Polyclonal Antibody |
别名 | DD3;DDX;HA1753;HAKRB;HAKRe;HSD17B5;PGFS;hluPGFS |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IP 1:50-100. |
Gene ID | 8644 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P42330 |
蛋白分子量 | 37kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm |
免疫原 | Recombinant protein of human AKR1C3 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. |
Public Immunogen Range | Recombinant protein of human AKR1C3 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanMouse |
应用 | WBIF |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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