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产品简介
| 英文名称 | Anti-IL12RB1 Polyclonal Antibody |
| 别名 | CD212;IL-12R-BETA1;IL12RB;IMD30 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IF 1:10-100. |
| Gene ID | 3594 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P42701 |
| 蛋白分子量 | 73kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Membrane Single-pass type I membrane protein |
| 免疫原 | Recombinant protein of human IL12RB1 |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. |
| Public Immunogen Range | Recombinant protein of human IL12RB1 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WBIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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