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产品简介
| 英文名称 | Anti-ACVR2A Polyclonal Antibody |
| 别名 | ACTRII;ACVR2 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:100-200. IF 1:50-200. |
| Gene ID | 92 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P27037 |
| 蛋白分子量 | 58kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Membrane Single-pass type I membrane protein |
| 免疫原 | Recombinant protein of human ACVR2A |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. |
| Public Immunogen Range | Recombinant protein of human ACVR2A |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIFIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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