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产品简介
英文名称 | Anti-PSMD2 Polyclonal Antibody |
别名 | P97;RPN1;S2;TRAP2 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
Gene ID | 5708 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q13200 |
蛋白分子量 | 100kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytosol secreted Nucleus |
免疫原 | Recombinant protein of human PSMD2 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene. |
Public Immunogen Range | Recombinant protein of human PSMD2 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanMouse |
应用 | WBIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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