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产品名称
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起订数量
产品简介
英文名称 | Anti-CDKN2C Polyclonal Antibody |
靶标 | CDKN2C |
别名 | INK4C;p18;p18-INK4C |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-100. IF 1:50-100. |
Gene ID | 1031 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P42773 |
蛋白分子量 | 18kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Nucleus |
免疫原 | Recombinant protein of human CDKN2C |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. |
Public Immunogen Range | Recombinant protein of human CDKN2C |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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