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产品简介
英文名称 | Anti-SLAMF1 Polyclonal Antibody |
别名 | CD150;CDw150;SLAM |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. |
Gene ID | 6504 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q13291 |
蛋白分子量 | 37kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Membrane Secreted |
免疫原 | Recombinant protein of human SLAMF1 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | Following occupancy of the T cell receptor by antigen, T cell proliferation and lymphokine production are determined by a second costimulatory signal delivered by a ligand expressed on antigen-presenting cells. SLAM (for signaling lymphocyte-activation molecule, also designated CDw150) is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SAP (for SLAM-associated protein) contains an SH2 domain and functions to inhibit SH-PTP2 recruitment to the SLAM docking site, an activity induced by Fyn phosphorylation of SLAM. Mutations of the SAP gene may be associated with X-linked lympho-proliferative disease (XLP). |
Public Immunogen Range | Recombinant protein of human SLAMF1 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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