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产品简介
英文名称 | Anti-PIN1 Polyclonal Antibody |
别名 | DOD;UBL5;peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-200. |
Gene ID | 5300 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q13526 |
蛋白分子量 | 18kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Nucleus |
免疫原 | Recombinant protein of human PIN1 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene. |
Public Immunogen Range | Recombinant protein of human PIN1 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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