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产品简介
英文名称 | Anti-SPDYA Polyclonal Antibody |
别名 | RINGO3;RINGOA;SPDY1;SPY1 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. |
Gene ID | 245711 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q5MJ70 |
蛋白分子量 | 36kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Nucleus |
免疫原 | Recombinant protein of human SPDYA |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | Speedy A, also known as SPDYA, SPDY1, Ringo3 or SPY1, is a 313 amino acid protein that localizes to the nucleus and belongs to the speedy/ringo family. Expressed at high levels in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver spleen and placenta, Speedy A functions to regulate the G1/S phase transition of the cell cycle, specifically by binding to and activating Cdc2 p34, Cdk2 and p27. Additionally, Speedy A mediates cell survival during DNA damage, suggesting that Speedy A plays a role in proper cell cycle progression throughout the life of the cell. Multiple isoforms of Speedy A exist due to alternative splicing events. The gene encoding Speedy A maps to human chromosome 2, which encodes over 1,400 genes and comprises nearly 8% of the human genome. |
Public Immunogen Range | Recombinant protein of human SPDYA |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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