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产品简介
英文名称 | Anti-ATF2 Polyclonal Antibody |
别名 | CRE-BP1;CREB-2;CREB2;HB16;TREB7 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
Gene ID | 1386 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P15336 |
蛋白分子量 | 55kDa |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Mitochondrion outer membrane Nucleus |
免疫原 | Recombinant protein of human ATF2 |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene |
Public Immunogen Range | Recombinant protein of human ATF2 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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