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产品简介
| 英文名称 | Anti-COCH Polyclonal Antibody |
| 别名 | COCH-5B2;COCH5B2;DFNA9 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. IF 1:50-100. |
| Gene ID | 1690 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O43405 |
| 蛋白分子量 | 59kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Secreted extracellular matrix extracellular space |
| 免疫原 | Recombinant protein of human COCH |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. |
| Public Immunogen Range | Recombinant protein of human COCH |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | IHCIF |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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