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产品简介
| 英文名称 | Anti-ATP6V1B1 Polyclonal Antibody |
| 别名 | ATP6B1;RTA1B;VATB;VMA2;VPP3 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. |
| Gene ID | 525 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P15313 |
| 蛋白分子量 | 57kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Endomembrane system Peripheral membrane protein |
| 免疫原 | Recombinant protein of human ATP6V1B1 |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. |
| Public Immunogen Range | Recombinant protein of human ATP6V1B1 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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