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产品简介
| 英文名称 | Anti-C5 Polyclonal Antibody |
| 别名 | C5D;C5a;C5b;CPAMD4;ECLZB |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. IF 1:50-100. |
| Gene ID | 727 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P01031 |
| 蛋白分子量 | 188kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Secreted |
| 免疫原 | Recombinant protein of human C5 |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants. |
| Public Immunogen Range | Recombinant protein of human C5 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIFIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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