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产品简介
| 英文名称 | Anti-HIRA Polyclonal Antibody |
| 别名 | DGCR1;TUP1;TUPLE1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:100-200. |
| Gene ID | 7290 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P54198 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 112/89kDa |
| 亚细胞定位 | Nucleus PML body |
| 免疫原 | Recombinant protein of human HIRA |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. |
| Public Immunogen Range | Recombinant protein of human HIRA |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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