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产品简介
| 英文名称 | Anti-CD33 Polyclonal Antibody |
| 别名 | p67;SIGLEC3;SIGLEC-3 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| Gene ID | 945 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P20138 |
| 蛋白分子量 | 40kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human CD33 |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | CD33?or Siglec-3 is a?transmembrane receptor?expressed on cells of?myeloid?lineage.?It is usually considered myeloid-specific, but it can also be found on some?lymphoid?cells. Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. |
| Public Immunogen Range | Recombinant protein of human CD33 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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