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产品简介
| 英文名称 | Anti-SKIL Polyclonal Antibody |
| 别名 | SNO;SnoA;SnoI;SnoN |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:200-1000. IHC 1:10-100. |
| Gene ID | 6498 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P12757 |
| 蛋白分子量 | 77kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human SKIL |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. |
| Public Immunogen Range | Recombinant protein of human SKIL |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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