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产品简介
| 英文名称 | Anti-CASR Polyclonal Antibody |
| 别名 | CAR;FHH;FIH;HHC;EIG8;HHC1;NSHPT;PCAR1;GPRC2A;HYPOC1 |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:25-100. |
| Gene ID | 846 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P41180 |
| 蛋白分子量 | 121kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane |
| 免疫原 | Recombinant protein of human CASR |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. |
| Public Immunogen Range | Recombinant protein of human CASR |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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